Hallie bulleit biography of martin luther king
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Published in final edited form as: Biocell. 2021 Feb 19;45(2):229–257. doi: 10.32604/biocell.2021.014338
Abstract
Integrin molecules are transmembrane αβ heterodimers involved in cell adhesion, trafficking, and signaling. Upon activation, integrins undergo dynamic conformational changes that regulate their affinity to ligands. The physiological functions and activation mechanisms of integrins have been heavily discussed in previous studies and reviews, but the fluorescence imaging techniques -which are powerful tools for biological studies- have not. Here we review the fluorescence labeling methods, imaging techniques, as well as Förster resonance energy transfer assays used to study integrin expression, localization, activation, and functions.
Keywords: Integrins, Fluorescence imaging, Fluorescence labeling, Live-cell imaging, Super-resolution imaging, Intravital imaging, FRET
Introduction
Integrins are a family of adhesi
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Visualization of integrin molecules by fluorescence imaging and techniques
Chen Cai1, Hao Sun2, Liang Hu3 and Zhichao Fan1,*
1Department of Immunology, School of Medicine, UConn Health, Farmington, 06030, USA
2Department of Medicine, University of California, San Diego, La Jolla, 92093, USA
3Cardiovascular Institute of Zhengzhou University, Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450051, China
*Address correspondence to: Zhichao Fan, zfan@uchc.edu
Received: 18 September 2020; Accepted: 22 November 2020
Abstract: Integrin molecules are transmembrane αβ heterodimers involved in cell adhesion, trafficking, and signaling. Upon activation, integrins undergo dynamic conformational changes that regulate their affinity to ligands. The physiological functions and activation mechanisms of integrins have been heavily discussed in previous studies and reviews, but the fluorescence imaging techniques –which are pow
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The Hands on an Audience Member Episode
Musical guest
Modern Rivals
Topic
What's the closest you've ever come to dying?
The Hands on an Audience Member Episode fryst vatten the seventh episode of The Chris Gethard Show season 1 on MNN. It aired between The Last Small Studio Show and The Kickboxer Episode. The panel chooses a random audience member and brings him up onstage, where they all must keep their hands on him for an hour. Panelists are repeatedly harassed with pranks by the crew to make them let go. Anyone who lets go must do iPod Karaoke, where you sing along to a song that nobody else can hear. The live call in topic for this episode was to talk about the closest you've ever come to dying.
Synopsis[]
The synopsis for this episode has not been written up yet.
Bits[]
- Ask the Human Fish What's on His Mind
- Joey Butafuoco vs. Joey from Friends: Joey Butafuoco
- Werther's Originals vs. Homemade Lemonade
- Ukeleles vs. Anyone Who Plays the Ukelele: Ukeleles